Dear Colleague,
On behalf of the Organizing Committee, it gives us great pleasure to invite you to the International Symposium on Pharmacogenomics in Epilepsy to be held in Hirosaki, Japan in association with the 43rd Congress of the Japan Epilepsy Society.
Research on the Pharmacogenomics in Epilepsy has entered a period of mushrooming growth, and Hirosaki has the longest history of epilepsy research in Japan. For these reasons, we are convinced that this is a perfect time to be holding the first Symposium in Japan on Pharmacogenomics in Epilepsy in Hirosaki.
Much is to be gained from this gathering of leading doctors and scientists in this field to report new advances, to review processes, discuss conflicting findings and divergent interpretations on CYP and transporter genotypic-phenotypic responses, to discuss significant implications of polymorphisms in drug target sites, and lastly to make more meaningful plans for the future directions of research.
The selection of drug treatments for epilepsy is still based upon trial-error strategies. Pharmacogenomics tries to identify possible genetic determinants of clinical responses and can help to predict clinical outcome even before treatments are commenced. Though genetic information will never solve all of the puzzles facing us in this field, nothing will be clarified without it. Thus, we cannot overstress the need for fruitful collaboration among clinicians, clinical pharmacologists, and molecular biologists. This International Symposium will be a basis for the development of individualized medicine for epilepsy in the future.
Hirosaki is a small, traditional castle town with a relaxing park. Some call it "small Kyoto," in recognition of its many temples and very good Japanese gardens. Places to visit, when you come Hirosaki, include Mt Iwaki, Lake Towada, and of course the gardens.
The Organizing Committee looks forward to welcoming you to Hirosaki in 2009. We hope that you will benefit from the scientific program, share information and ideas with new acquaintances, and enjoy your stay in one of beautiful cities in Japan.
With warm regards,
- Sunao Kaneko MD., PhD
- International Symposium on Pharmacogenomics in Epilepsy
- Professor and Chairman
- Department of Neuropsychiatry, Hirosaki University
- Graduate School of Medicine
Date
- The 43rd Congress of the Japan Epilepsy Society
- from 22nd to 23rd, October, 2009
- The International Symposium on Pharmacogenomics in Epilepsy
- 24th October, 2009
Venue
Hirosaki Hotel New Castle
Hirosaki Hotel New Castle is located at the center of Hirosaki nearby Hirosaki Park, the attraction for which Hirosaki is famous.
24-1, Kamisayashi-machi, Hirosaki 036-8354, Japan Phone: +81-172-36-1211 Fax: +81-172-33-4577
October 24 (Saturday), 2009
Opening Remarks 8:00 - 8:05
- Sunao Kaneko
- Dept. of Neuropsychiatry, Hirosaki University Graduate School of Medicine, Japan
Introduction 8:05 - 8:35 Hall A
Chair :
- Sunao Kaneko
- Dept. of Neuropsychiatry, Hirosaki University Graduate School of Medicine, Japan
Speaker :
- I -1
- "Are drug resistant and drug sensitive patients the same"
- Martin J Brodie
- Epilepsy Unit, Division of Cardiovascular and Medical Sciences, Western Infirmary, Glasgow, UK
Symposium 1 "Genetics in Epilepsy" 8:35 - 10:05 Hall A
Chair :
- Sung-Eun Kim
- Dept. of Neurology, Inje Paik Hospital at Busan, Korea
- Kazuhiro Yamakawa
- Laboratory for Neurogenetics, RIKEN Brain Science Institute, Japan
Speaker :
- S1-1
- "Molecular Pathogenesis of Epilepsies"
- Shinichi Hirose
- Dept. of Pediatrics, Fukuoka University School of Medicine, Japan
- S1-2
- "Genetics of JME"
- Kazuhiro Yamakawa
- Laboratory for Neurogenetics, RIKEN Brain Science Institute, Japan
- S1-3
- "Genetics of Isolated Epilepsies"
- Toshio Kojima
- Synthetic Biology Team, Computational Systems Biology Research Group,
RIKEN Advanced Science Institute, Japan
Coffee break 10:05 - 10:30 Hall B
Symposium 2 "Phamacodynamics in Epilepsy" 10:30 - 12:00 Hall A
Chair :
- Jeffrey L. Noebels
- Dept. of Neurology, Baylor College of Medicine, Houston, Texas, U.S.A
- Yoshiya L Murashima
- Tokyo Metropolitan University Graduate School
Speaker :
- S2-1
- "Mechanisms of Action of AEDs"
- Gang Zhu
- The First Hospital of China Medical University, Shenyang, China
- S2-2
- "Epilepsy Model Animals"
- Motohiro Okada
- Dept. of Neurosurgery, Division of Neuroscience, Graduate School of Medicine, Mie University, Japan
- S2-3
- "Molecular Target in the Brain"
- Jeffrey L. Noebels
- Dept. of Neurology, Baylor College of Medicine, Houston, Texas, U.S.A.
Poster session & Lunch 12:00 - 13:00 Hall B
Symposium 3 "Phamacokinetics in Epilepsy" 13:00 - 15:00 Hall A
Chair :
- Kazuko Nakagawa
- Division of Pharmacology and Therapeutics, Graduate School of Medical and Pharmaceutical Science, Kumamoto University, Japan
- Yuan-Tsong Chen
- Institute of Biomedical Sciences, Taiwan
Dept. of Dermatology, Rheumatology, Allergy, and Immunology, and Nephrology, Chang Gung Memorial Hospital, Taiwan
Speaker :
- S3-1
- "Steven-Jhonson Syndrome and Related Diseases"
- Yuan-Tsong Chen
- Institute of Biomedical Sciences, Taiwan
Dept. of Dermatology, Rheumatology, Allergy, and Immunology, and Nephrology, Chang Gung Memorial Hospital, Taiwan
- S3-2
- "Polymorphisms of CYP and Ethnic Difference"
- Tomonori Tateishi
- Pharmaceuticals and Medical Devices Agency
- S3-3
- "Polymorphisms of Transporters and Ethnic Difference"
- Sanjay Sisodiya
- Dept. of Clinical and Experimental Epilepsy, UCL
Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, UK
- S3-4
- "Phamacogenetics and Epilepsy Treatment"
- Junji Saruwatari
- Division of Pharmacology and Therapeutics, Graduate School of Medical and Pharmaceutical Science, Kumamoto University, Japan
Symposium 4 "Tailor-made Phamacotherapy in Epilepsy" 15:00 - 16:00 Hall A
Chair :
- Sanjay Sisodiya
- Dept. of Clinical and Experimental Epilepsy, UCL
Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, UK - Shigeru Motomura
- Department of Pharmacology, Hirosaki University Graduate School of Medicine
Speaker :
- S4-1
- "The Clinical and Genetic Factors Predicting the Responsible to AEDs"
- Sung-Eun Kim
- Dept. of Neurology, Inje Paik Hospital at Busan, Korea
- S4-2
- "Development of Individualized Medicine for Epilepsy Based on Genetic Information"
- Sunao Kaneko
- Dept. of Neuropsychiatry, Hirosaki University Graduate School of Medicine, Japan
Closing Remarks 16:00 - 16:05 Hall A
- Hiroto Iwasa
- Aomori Prefectural Center for Mental Health and Welfare;
Department of Neuropsychiatry, Hirosaki University Graduate School of Medicine, Japan
Organizing Committee
Chairman
- Sunao Kaneko
- Department of Neuropsychiatry, Hirosaki University Graduate School of Medicine
Secretary General
- Hiroto Iwasa
- Aomori Prefectural Center for Mental Health and Welfare;
Department of Neuropsychiatry, Hirosaki University Graduate School of Medicine - Kazumaru Wada
- Department of Disability and Health, Division of Health Sciences,
Hirosaki University Graduate School of Health Sciences
Organizers
- Shigeru Motomura
- Department of Pharmacology, Hirosaki University Graduate School of Medicine
- Tatsuya Tanaka
- President of Japan Epilepsy Society
Dept. of Neurosurgery, Asahikawa Medical College
Secretariat
- Akiko Iwasaki
- Department of Neuropsychiatry, Hirosaki University Graduate School of Medicine
c/o Convention Linkage, Inc. Sanbancho KS Bldg., 2 Sanbancho, Chiyoda-ku Tokyo 102-0075, JAPAN
Phone:+81-3-3263-8688 Fax: +81-3-3263-8693 E-mail: jes43@c-linkage.co.jp
| Name* | Title | Affiliation | Provisional topics |
|---|---|---|---|
| Martin J Brodie | Professor | Epilepsy Unit, Division of Cardiovascular and Medical Sciences, Western Infirmary, Glasgow G11 6NT, Scotland, UK | "Are drug resistant and drug sensitive patients the same" |
Yuan-Tsong Chen |
Professor | Institute of Biomedical Sciences, Academia Sinica, Taiwan Departments of Dermatology, Rheumatology, Allergy, and Immunology, and Nephrology, Chang Gung Memorial Hospital, Taiwan |
Genetic Susceptibility and Pharmacogenomics of Drug Hypersensitivity Reactions. |
| Shinichi Hirose | Professor | Dept. of Pediatrics, Fukuoka University School of Medicine, Japan | "Epilepsy Model Animals" |
| Sunao Kaneko | Professor | Dept. of Neuropsychiatry, Hirosaki University Graduate School of Medicine, Japan | "Development of Individualized Medicine for Epilepsy Based on Genetic Information" |
| Sung-Eun Kim | Professor | Dept. of Neurology, Inje Paik Hospital at Busan, Korea | "The Clinical and Genetic Factors Predicting the Responsible to AEDs" |
| Toshio Kojima | Sub Team leader | Synthetic Biology Team, Computational Systems Biology Research Group, RIKEN Advanced Science Institute, Japan | "Genetics of Isolated Epilepsies" |
| Kazuko Nakagawa | Professor | Division of Pharmacology and Therapeutics, Graduate School of Medical and Pharmaceutical Science, Kumamoto University, Japan | "Phamacogenomics and Epilepsy Treatment" |
| Jeffrey L. Noebels | Professor | Dept. of Neurology, Baylor College of Medicine, Houston, Texas, U.S.A. | "Molecular Target in the Brain" |
| Motohiro Okada | Professor | Dept. of Neurosurgery, Division of Neuroscience, Graduate School of Medicine, Mie University, Japan | "Molecular Pathogenesis of Epilepsies" |
| Sanjay Sisodiya | Professor | Dept. of Clinical and Experimental Epilepsy, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, UK | "Polymorphisms of Transporters and Ethnic Difference" |
| Tomonori Tateishi | Professor | Dept. of Clinical Pharmacology, Hirosaki University Graduate School of Medicine, Japan | "Genetic Polymorphisms of CYP and Ethnic Difference" |
| Kazuhiro Yamakawa | Team leader | Laboratory for Neurogenetics, RIKEN Brain Science Institute, Japan | "Genetics of JME" |
| Gang Zhu | Professor | The First Hospital of China Medical University, Shenyang, China | "Mechanisms of Action of AEDs" |
* Invited faculties listed alphabetically by name.